Transcatheter successful palliation of a newborn with ductal-dependent pulmonary circulation
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Case Report
VOLUME: 5 ISSUE: 2
P: 34 - 36
June 2017

Transcatheter successful palliation of a newborn with ductal-dependent pulmonary circulation

J Updates Cardiovasc Med 2017;5(2):34-36
1. Dr.Sami Ulus Maternity and Children Research and Training Hospital,Department of Pediatric Cardiology, Specialist Dr., Ankara, Turkey
2. Dr.Sami Ulus Maternity and Children Research and Training Hospital,Department of Pediatric Cardiology, Assoc. Dr., Ankara, Turkey
3. Dr.Sami Ulus Maternity and Children Research and Training Hospital,Department of Pediatric Cardiology, Prof. Dr., Ankara, Turkey
No information available.
No information available
Received Date: 08.10.2016
Accepted Date: 25.02.2017
Publish Date: 15.06.2017
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Introduction

Conventional management of neonates with ductal-dependent pulmonary flow entails maintaining ductal patency using prostaglandin E1 infusion followed by surgical palliation with BlalockTaussig shunt (B-T shunt). Nowadays, percutaneous transcatheter placement of a stent to maintain ductal patency has been used as an alternative method to provide a source of pulmonary blood flow.[1,2] The potential advantages of ductal stenting include reduced procedure-related risks and improved distribution of pulmonary artery blood flow.[3] Ductal stenting could be used as a bridge toward corrective surgery in neonates.[4]

Case Report

A two-day-old boy was referred to our hospital for cardiac evaluation moderate to severe cyanosis (percutaneous oxygen saturation 60%). Echocardiography showed, situs solitus, levocardia, concordant atrioventricular connection, large outlet ventricular septal defect, pulmonary atresia, hypoplastic pulmonary artery branches, right aortic arch and vertical arterial duct. Cardiac catheterization was performed via right femoral vein. Pulmonary artery branches were hypoplastic (right and left pulmonary artery 3 mm) and supplied by a vertical, tortuous ductus with distal narrowing which arises from the inner curve of a right sided aortic. (Figure 1) Firstly distal narrowed part of ductus arteriosus was stented with a coronary stent (4×15 mm) (Figure 2).

After that a second coronary stent (4×15 mm) was implanted to cover most of the duct (Figure 3). The final oxygen saturation was 90% after two stent implantation. After cessation of prostaglandin infusion the patient’ oxygen saturation gradually decreased up to the 55%. Second cardiac catheterization showed critically stenosis in aortic end of ductus (Figure 4).

A third coronary stent (4×15 mm) was placed to cover the aortic side entirely (Figure 5). The oxygen saturation was increased to 85% after third stent implantation. The patient was discharged with %85 oxygen saturation in the following days. During follow-up periods of to three months he had no problem clinically, weight gain and %88 percutaneous oxygen saturation.

Discussion

Ductal stenting a reliable and more physiologic alternative to surgical systemic to pulmonary shunt in neonates.  But the lack of stent coverage of the entire ductus (especially in long and tortuous duct) results duct constriction and cyanosis of the patient and causes re-intervention in most cases. It is well known that passing a catheter through the stent is technically very difficult and increases the risk of thrombosis and hemodynamic destabilization when compared with the primary intervention. Therefore stent long must be enough to cover entire ductus. But in some cases a small segment of the duct may be left uncovered and necessitating use of second or third stent. The full-length stenting of the duct without leaving any ductal tissue is important.

References

1
Alwi M, Choo KK, Haifa AL, Geetha K, Hasri S, Mulyadi MD. Initial results and medium-term follow-up of stent implantation of patent ductus arteriosus in duct-dependent pulmonary circulation. J Am Coll Cardiol. 2004;44:438–45.
2
Gewillig M, Boshoff DE, Dens J, Mertens L, Benson LN. Stenting the neonatal arterial duct in duct-dependent pulmonary circulation:New techniques, better results. J Am Coll Cardiol 2004;43:107–112.
3
McMullan DM, Permut LC , Jones TK, Troy Alan Johnston TA, Rubio AE. Modified Blalock-Taussig shunt versus ductal stenting for palliation of cardiac lesions with inadequate pulmonary blood flow. J Thorac Cardiovasc Surg 2014;147:397-403.
4
Santoro G, Gaio G, Castaldi B, et al. Arterial Duct Stenting in Low-Weight Newborns With Duct-Dependent Pulmonary Circulation. Catheterization and Cardiovascular Interventions. 2011; 78:677–685.